Tiletamine-zolazepam is best for aggressive patients requiring rapid knockdown in a facility that can handle a prolonged recovery.

• A. True
• B. False
• C. Not applicable
• D. Only for dogs

Answer: (A)

Tiletamine-zolazepam brings rapid onset and strong immobilization because tiletamine is a dissociative anesthetic that quickly disrupts awareness and reflexes, while zolazepam provides muscle relaxation and smoother induction and recovery. This combination is especially useful when you must rapidly control an aggressive or fractious patient. However, recoveries can be prolonged and variable, and there’s no simple reversal for the mixture, so you need a facility that can closely monitor and manage a longer emergence. In that context, this drug is the best choice for a setting that can handle a prolonged recovery, which is why the statement is true.