Which is a common gastrointestinal side effect of opioids?

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Multiple Choice

Which is a common gastrointestinal side effect of opioids?

Explanation:
Opioids commonly trigger nausea and vomiting because they activate receptors in the brain’s chemoreceptor trigger zone and can affect vestibular pathways, especially with initial dosing or dose changes. They also slow gastrointestinal motility, which often leads to constipation, another well-known opioid effect. Diarrhea and heartburn are not typical opioid-induced GI effects, and weight gain isn’t a direct GI side effect of opioid analgesia. So nausea and/or vomiting best fits the common gastrointestinal response to opioids.

Opioids commonly trigger nausea and vomiting because they activate receptors in the brain’s chemoreceptor trigger zone and can affect vestibular pathways, especially with initial dosing or dose changes. They also slow gastrointestinal motility, which often leads to constipation, another well-known opioid effect. Diarrhea and heartburn are not typical opioid-induced GI effects, and weight gain isn’t a direct GI side effect of opioid analgesia. So nausea and/or vomiting best fits the common gastrointestinal response to opioids.

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